When a two-billion-year-old life form threatens to destroy the human Y chromosome, the brilliant molecular biologist Dr. Sophie Tesla, aka God, must save the men from extinction, beginning with a washed-up, alcoholic jazz drummer accused of murder.
Harry Cain, aka Y chromosome N007, soon realizes he was safer behind bars. Sophie leads him into the dangerous world of jealous boyfriends, CIA assassins and prizefighting Roma gypsies as she battles her greatest nemesis, the deadly bacteria known as Wolbachia N42.