購物比價找書網找車網
FindBook  
 有 1 項符合

Frances Oldham Kelsey, the Fda, and the Battle Against Thalidomide

的圖書
Frances Oldham Kelsey, the Fda, and the Battle Against Thalidomide Frances Oldham Kelsey, the Fda, and the Battle Against Thalidomide

作者:Warsh 
出版社:Oxford University Press, USA
出版日期:2024-05-21
語言:英文   規格:精裝 / 288頁 / 普通級/ 初版
圖書選購
型式價格供應商所屬目錄
 
$ 1575
博客來 博客來
女性主義與理論
圖書介紹 - 資料來源:博客來   評分:
圖書名稱:Frances Oldham Kelsey, the Fda, and the Battle Against Thalidomide

內容簡介

The woman scientist who saved Americans from thalidomide

In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, a drug routinely given to pregnant women to prevent morning sickness.

As the FDA medical officer charged with reviewing Merrell Pharmaceutical’s application for approval in 1960-61, Kelsey was unconvinced that there was sufficient evidence of the drug’s efficacy and safety. Despite substantial pressure, she held her ground for nineteen months while the extent of the drug’s worldwide damage became known-thousands of stillborn babies, as well as at least 10,000 children across 46 countries born with severe deformities such as missing limbs, arms and legs that resembled flippers, and improperly developed eyes, ears, and other organs.

As a result of Kelsey’s efforts, thalidomide was never sold in the United States. The incident led Congress to pass the 1962 Drug Amendment, which fundamentally changed drug regulation in America. Those regulations, still in force today, required pharmaceutical companies to conduct phased clinical trials, obtain informed consent from participants in drug testing, and warn the FDA of adverse effects, and it granted the FDA important controls over prescription-drug advertising.

One of a small minority of women to earn an advanced degree in science in the 1930s, Kelsey faced challenges that resonate with women scientists to this day. Revered by the public as a "good mother of science," she went on to act as a formidable gatekeeper against other suspect drugs, such as diesthylstilbestrol (DES) and laetrile. As part of the team that tested anti-malarial drugs on prisoner volunteers during World War II, she later was instrumental in the formulation of ethical protocols for drug testing on prisoners and the vulnerable, including the elderly and children. Yet behind the public adulation, she faced professional jealousies and glass ceilings, political interference with FDA’s actions, and ongoing hostility from pharmaceutical industry officials. She was sustained and supported by family and friends, co-workers and mentors, and a lifetime commitment to good science.

Based upon FDA archival records, private family papers, and interviews with family and colleagues, this biography brings to light the efforts and legacy of a pioneering woman of science whose contributions are still influential today.

 

作者簡介


Cheryl Krasnick Warsh is Professor of History at Vancouver Island University in Nanaimo, Canada. Dr. Warsh has published books on the history of asylums, women’s health, children’s health, consumerism, and alcohol and drug use. She served as long-term editor-in-chief of the Canadian Bulletin of Medical History and was co-editor of Gender & History. Dr. Warsh was a Fulbright Fellow, AMS/Hannah Fellow, and the inaugural recipient of the Vancouver Island University Distinguished Researcher Award. In 2017, she was elected a Fellow of the Royal Society of Canada for her contributions to Canadian medical history.

 

詳細資料

  • ISBN:9780197632543
  • 規格:精裝 / 288頁 / 普通級 / 初版
  • 出版地:美國
贊助商廣告
 
金石堂 - 今日66折
黑馬飆股操作攻防術:阿文師的快速致富指南
66折: $ 211 
金石堂 - 今日66折
一次戰勝新制多益TOEIC必考聽力攻略+解析+模擬試題(2書裝+1CD)
作者:SINAGONG多益專門小組等
出版社:時報文化出版企業股份有限公司
出版日期:2019-08-27
66折: $ 395 
 
金石堂 - 暢銷排行榜
pop one`s cherry(01)
作者:百合アズル
出版社:尖端漫畫
出版日期:2025-05-20
$ 119 
金石堂 - 暢銷排行榜
說謊是因為喜歡你-全
作者:アヒル森下
出版社:長鴻出版社股份有限公司
出版日期:2025-05-23
$ 126 
博客來 - 暢銷排行榜
窮查理的普通常識(紀念典藏版):巴菲特50年智慧合夥人查理.蒙格的人生哲學
作者:查理.蒙格 (Charles T. Munger)
出版社:商業周刊
出版日期:2024-04-30
$ 395 
Taaze 讀冊生活 - 暢銷排行榜
納瓦爾寶典珍藏版︰從白手起家到財務自由,矽谷傳奇創投家的投資哲學與人生智慧
作者:艾瑞克.喬根森
出版社:天下雜誌股份有限公司
出版日期:2025-02-05
$ 355 
 
金石堂 - 新書排行榜
新.朋友的馬麻(中) 無修正
作者:gonza
出版社:未來數位有限公司
出版日期:2025-05-02
$ 261 
金石堂 - 新書排行榜
聽見向陽之聲–春夏秋冬–(03)
作者:文乃 ゆき
出版社:尖端漫畫
出版日期:2025-05-16
$ 213 
博客來 - 新書排行榜
與人為善的幸福哲學:吳家德的豐盛人生心法
作者:吳家德
出版社:遠流
出版日期:2025-04-17
$ 300 
博客來 - 新書排行榜
狼與辛香料 完全版 (5)
$ 300 
 

©2025 FindBook.com.tw -  購物比價  找書網  找車網  服務條款  隱私權政策