In Tapisco Valley, a town divided by class and the Lehigh River, there live two best friends struggling with poverty. Devin Miles and Tyler Holmes sell weed to support their families while dealing with deep-rooted prejudices in their town. Devin soon finds Storm, a Native American girl who deals with her depression and anxiety through art and poetry. Meanwhile, another drug dealer from the rich side of town, Damien Banks, starts stealing Tyler and Devin’s business that they desperately need to survive. The Art of the Damned is a look into the American life and dream of those damned by society.