Bioprocess Engineering and Technology: Upstream Process

This book discusses the various cellular interventions that are required for the upstream processes in bioprocess engineering such as growth requirement of different cell types, their maintenance, and various recombinant strategies/tools available to identify and develop a cellular factory for high-level synthesis of a desired product. Bioprocess Engineering and Technology: Upstream Process also deals with the various types of reactors, process design and development (media, conditions, mode of operation, sterilisation, selectivity), reactor design and construction, scale-up, process analytical technologies, and process control. The book examines upstream processes which include the selection of cell factories and strain engineering approaches, enzyme kinetics, growth kinetics, fermentation, downstream processing, process design, reactor design, and scale-up. It also includes case studies that will assist readers to develop the upstream processes involved in an industrial-scale bioprocess.

This book is intended for students and researchers looking to develop the upstream processes involved in an industrial-scale bioprocessing operation.

Dr. Biswanath Bhunia is an Assistant Professor at the Department of Bioengineering, National Institute of Technology Agartala, India.

Dr. Navneet Joshi is presently working as Professor, Department of Bioscience, School of Liberal Arts and Sciences, Mody University of Science and Technology, Lakshmangarh, Sikar, Rajasthan, India. He did his Ph.D on molecular characterization of microbial isolates with industrial applications and their cyto-morphological analysis under heavy metal abiotic stress from University of Rajasthan India. His research area is associated with microbial bioprocess biotechnology/plant biotechnology & molecular biology with special reference to molecular characterization of industrial isolates.

Muthusivaramapandian Muthuraj is at the Department of Bioengineering, National Institute of Technology Agartala National Institute of Technology Agartala.