Histochemical and Immunohistochemical Techniques: Applications to Pharmacology and Toxicology

1 Why use histochemistry for a better understanding of pharmacology and toxicology?.- 2 Whole-body autoradiography of pharmaceuticals and chemicals.- 3 Image analysis, fluorescence and laser microscopy.- 4 The measurement of free calcium to assess cellular function and injury using digital imaging fluorescence microscopy.- 5 Flow cytometry to characterize normal and abnormal cell function.- 6 Quantitative histochemical and cytochemical assays.- 7 Fixation of tissue for histochemistry.- 8 Immunochemical methods to assess cellular malfunction.- 9 Cell markers and processes related to chemically induced carcinogenesis.- 10 The mechanistic basis of chemical- and drug-induced nephrotoxicity.- 11 Pollutant-induced toxicity in the marine environment.