Approaches to Gene Mapping in Complex Human Disease

Approaches to Gene Mapping in Complex Human Diseases Edited by Jonathan L. Haines and Margaret A. Pericak-Vance Recent years have seen a tremendous growth in statistical and laboratory methods for genetic mapping -a process by which we discover genes that contribute to heart disease, hypertension, diabetes, asthma, cancer, and other complex genetic disorders not controlled by a single gene. Approaches to Gene Mapping in Complex Human Diseases is the first book devoted to the analysis of such common, inherited diseases. This text helps the reader sort through the plethora of available resources, choose the best methodology for a given problem, and design successful gene mapping projects from the ground up. In eighteen chapters, compiled by two of the leading figures in the field, this book covers a wide range of topics -from the process of selecting families to the testing of candidate genes.