Human Molecular Genetics

Strachan (human molecular genetics, Newcastle U., UK) and Read (human genetics, Manchester U., UK) present a textbook for upper level undergraduates and graduate students that provides an integrated approach to the molecular aspects of human genetics. They present a framework of principles rather than a list of facts, meant to bridge the gap between basic textbooks and the research literature. With much of the text rewritten, this edition has also been updated to integrate genomic technologies throughout and includes next generation sequencing. In addition, genetic testing, screening, approaches to therapy, personalized medicine, and disease models are combined in one section, and coverage of cell biology, including stem cells and cell therapy, gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics has been expanded, along with more detail on the major animal models used in genetic studies. Annotation 穢2010 Book News, Inc., Portland, OR (booknews.com)