Handbook of Novel Psychoactive Substances provides an overview of the challenges that clinicians face when dealing with NPS and discusses how the profile of patients and their socio-demographic characteristics frame the serious public health concern that NPS pose. Included are clinical cases from a general perspective, as well as the general account of symptoms, psychopathology, toxicity, and overall clinical management that NPS require. An essential reference for clinicians, this book brings together a diverse and esteemed group of authors to provide a clear and thorough introduction to the problem of NPS and the clinical consequences of this emerging phenomenon.