“Middlesex” is primarily a coming-of-age novel and a family saga. It chronicles the effect of a mutated gene on the three generations of a Greek family. Owing to that, momentous changes occur in the life of the protagonist.
Most of the scholars have often said that the novel deals with the themes such as rebirth, nature versus nature, people between men and women. The novel also investigates gender identity. There are several allusions to Greek mythology, depicting several creatures and a monster.
Ready Reference Treatise: Middlesex Copyright Chapter One: Introduction Chapter Two: Background Chapter Three: Plot Overview Chapter Four: Major Characters Chapter Five: Complete Summary Book One Book Two Book Three Book Four Chapter Six: Critical Analysis