Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back

The regulation of gene transcription by neuronal activity is evident in many neuronal processes, ranging from neural development and refinement of neuronal connections to learning and response to injury. This book illustrates key advances in the field of activity regulation of gene transcription. Specifically, it explores how signals are transmitted to the nucleus in response to neuronal activity, which genes are activated and how they are activated, and how these changes in gene expression alter neuronal function. The editor and authors cover a variety of methods and topics, including signal initiation and transduction to the nucleus and possible functions of the activity-regulated genes.