When a drug company CEO disappears in the hills of New England, his wife hires neophyte P.I. Harley Napoleon to find him. The plot deepens when Napoleon has a gun stuck in his face at the CEO's hunting cabin. Then the executive perishes in a questionable auto incident and patients at a nearby clinic die after getting a new Alzheimer's drug made by the CEO's firm. While solving the mystery, Napoleon winds up in the clutches of rogue G-men, dodges the local police chief, and teams reluctantly with an over-the-top female reporter.