Back in the swinging '60s, Neil Brewer and Virginia McClain were lovers. Four decades on, Neil is recovering from a heart attack and his thoughts return to Virginia, now the senior bacteriologist at R&P Labs. He suggests a romantic reunion but Virginia turns him down, only to find when Neil is murdered that he has left a substantial legacy to the lab. But there's a catch; to receive it, they must first solve a series of clues.
In the second R&P Labs mystery, the scientific quintet reluctantly embark on their treasure hunt and try to track down Neil's killer, as Ellis fends off the attentions of an amorous chocolatier, Mitch becomes a bodyguard and Rob discovers an unexpected talent for breaking and entering.