This book is a powerful addition to a developing literature informed by arts and humanities research carried out during the COVID-19 pandemic. Investigating the impacts of crisis governance and decision-making on people and populations, the book brings together microbial organisms and humans, children and data, decision-making and infection prevention, publics and process, global vaccine distribution and citizens’ juries. Through its eight chapters, the book stimulates broadly-drawn discussions about exceptional executive powers in an emergency, the role of trust, and the importance of the principles of good governance - such as selflessness, ethics, integrity, accountability and honesty in leadership. The lessons drawn out in this book will support future decision-makers in both ordinary times and extra-ordinary emergencies.