Chromosomal Mutagenesis

Great disparities exist between organisms with regard to the relative ease of chromosomal mutagenesis and manipulation. In this book, a team of experts provide a variety of chromosomal manipulation techniques and attempt to expand the genetic toolbox beyond model organisms. Following the format of the highly successful Methods in Molecular Biology(TM) format, each chapter offers step-by-step laboratory instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, this book covers state-of-the-art techniques that are staged to expand, if not revolutionize, genetic analysis in the long neglected and relevant cell types.