All kindergarten teacher Peyton Pearson wants is a nice, quiet life. Unfortunately, quiet isn't something she's had a lot of after tainted medicine turns her into a superhero. She's single, and saving the city from criminals—which is increasingly dangerous as the anti-superhero movement in St. Louis gains traction. Then there's her hot next door neighbor who makes her think super-dirty thoughts, and has no idea who she really is.
Police officer Dylan Wilson is trying to make the world safe by working to unmask all superheroes. When his sexy neighbor, Peyton, is evicted, Dylan offers her his spare room, unknowingly opening his home—and his heart—to the city's most reluctant superhero.