Private Detective Duncan Andrews is back, along with the usual gang: Robbie, Gina, Nick, and Daisy, the zombie bulldog! Duncan is trying to figure out how his boyfriend, Robbie, will fit in with the team now that he is no longer a ghost. That worry is soon set aside when Duncan accepts a new case to locate a missing young man named Graig Betz. Duncan soon learns Graig is part of a werewolf pack that is terrorizing Indianapolis. The pack is led by a witch, Ashley Campbell, an old rival of Gina’s. Duncan and his team must try to rescue and cure Graig and stop the wolf pack from destroying an entire city.