Losing the Weight Loss Meds: A 10-Week Playbook for Stopping Glp-1 Medications Without Regaining the Weight

Most people regain weight after weight loss medications. You don’t have to.

New weight loss medications like Ozempic(R), Wegovy(R), Mounjaro(R), and Zepbound(R) (known as GLP-1s) can help you lose weight, but research shows that without a plan, the weight almost always comes back if the prescription ends. Losing the Weight Loss Meds is the first playbook designed specifically to help you transition off medication -- and keep your hard-earned success for life.

Written by leading obesity experts Dr. Holly R. Wyatt and Dr. James O. Hill, Losing the Weight Loss Meds lays out a science- backed, 10-week program to replace medication with the power of food, physical activity, and mindstate. You’ll discover how to:

• Reset your appetite naturally with smart food strategies
• Use physical activity to restore and optimize metabolism
• Strengthen your mindstate to build resilience against cravings and setbacks
• Catch early signs of weight regain and stop it before it snowballs
• Create routines and environments that make success easier to sustain

Whether you’re preparing to stop medication now or later, or just beginning your weight loss journey, this playbook equips you with the tools to protect your progress and fully live the life you’ve worked so hard to create.

Dr. Holly Wyatt is a leading authority in weight loss and long-term weight management, with over 25 years of experience helping people not only achieve significant weight loss but also maintain it for life. Best known as the medical doctor on the hit TV show Extreme Weight Loss, Dr. Wyatt has guided countless individuals through dramatic transformations, using her expertise in metabolism, nutrition, and behavior change. Coauthor of the bestselling book State of Slim, she specializes in creating sustainable, science-based strategies that empower people to reset their metabolism, manage their appetite, and develop healthy, lasting habits.

Dr. Wyatt’s career is dedicated to helping people maintain their weight loss and improve their overall well-being by focusing on sustainable lifestyle changes rather than quick fixes. Whether through her clinical programs, media appearances, or one-on-one coaching, Dr. Wyatt’s practical, personalized approach inspires people to not just reach their weight goals, but to truly transform their health and their lives in the process.

Dr. James O. Hill is a world-renowned expert in obesity, nutrition, and weight management, with over 40 years of groundbreaking research and experience in the field. As the cofounder of the National Weight Control Registry, the largest study of individuals who have successfully maintained long-term weight loss, and coauthor of State of Slim, Dr. Hill has pioneered the understanding of sustainable weight loss. His work has been instrumental in developing evidence-based strategies that empower people to achieve lasting weight management through balanced nutrition, physical activity, and behavioral changes.

Dr. Hill has published over 700 peer-reviewed articles and is widely recognized for his contributions to public health, including shaping national policies on obesity prevention and management. His expertise has been featured in major media outlets, and his research has influenced health professionals and individuals worldwide. With a passion for translating science into actionable advice, Dr. Hill continues to help people live healthier, more fulfilling lives by providing practical, long-term solutions for weight maintenance and overall well-being.