In Rome, two dynamic European interpreters with differing generational views of men, love, and relationships agree on one thing-upholding their freedom and equality as women. All is torn asunder when they meet soulmates, opening the possibility that love can transcend traditional gender roles. Natalie is in her early 70s and Antonella in her mid-thirties. Their adventures, dialogues, mishaps, and funny situations with men, family, friends, and work relations allow them to grow, gain wisdom, and experience true fulfillment in their lives.