Clinical and Laboratory Medicine Textbook

This textbook describes several diseases and clinical conditions, from physiopathological mechanisms to main clinical pictures, highlighting the importance of laboratory medicine, with the aim to provide the necessary tools for guiding correct laboratory findings interpretation.

Indeed, it is now widely recognized that laboratory medicine has a pivotal role in clinical medicine, significantly influencing clinical decisions. Thus, it is crucial to understand and use laboratory data appropriately.

This book has the great advantage of describing each topic exhaustively in order to facilitate its understanding. Specifically, it describes both diseases with a high incidence in the population, such as Diabetes Mellitus, Cardiovascular Diseases, Dyslipidemias, and Autoimmune Diseases, as well as rare diseases, such as Hereditary Metabolic Diseases. In addition, unusual topics are treated, such as Clinical Biochemistry of the Mind, as well as hot topics, such as Biological Drugs, Biobanks, Health Technology Assessment, and Omics Sciences. Finally, the book includes a chapter on the new health emergency, the SARS-CoV-2 pandemic. Two appendices are provided at the end of the book: a table summarizing the reference range and decisional cut-off for the main laboratory parameters and instructions on performing a venous blood sample.

Doctor Marcello Ciaccio is a Full Professor of Clinical Biochemistry and Laboratory Medicine and Dean of the School of Medicine at the University of Palermo. He is the Director of the Institute of Clinical Biochemistry, Clinical Molecular Medicine and Clinical Laboratory Medicine, Department of Biomedicine, Neurosciences, and Advanced Diagnostics at the University of Palermo. He is also Director of the Department of Laboratory Medicine - A.O.U.P. Palermo ＂P. Giaccone＂. He was Past-President (2016-2017) and President-Elect (2024-2025) of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology - Laboratory Medicine (SIBioC). He is part of the Editorial Board of several peer-reviewed Journals, and he serves as a Reviewer for many prestigious Journals. He is the author of more than 400 scientific publications in national and international Journals.