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Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance o

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Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance o Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance o

作者:Gadamasetti 
出版社:Springer
出版日期:2024-11-24
語言:英文   規格:精裝 / 490頁 / 普通級/ 初版
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圖書名稱:Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance o
 

作者簡介

Stephen A. Kolodziej is an Associate Research Fellow in the Biotherapeutics Pharmaceutical Sciences division of Pfizer at the Chesterfield Missouri site. His group develops downstream manufacturing processes for biotherapeutic drug and vaccine candidates, specializing in protein conjugates. He made major contributions to process and product understanding on late-stage bacterial vaccine projects, including multivalent capsular polysaccharide conjugate vaccines against pneumococcus, staphylococcus, and meningococcus. He started his professional career as a medicinal chemist in Searle, Pharmacia, and then Pfizer developing novel small molecule candidates for the treatment of inflammation, cancer, and cardiovascular disease. He applied the tools of combinatorial chemistry to produce small libraries of candidates for evaluation in numerous preclinical programs and was a coinventor for Xalkori(R), an ALK inhibitor approved for the treatment of non-small cell lung cancer. Steve has a BA and a PhD in Organic Chemistry from the University of Missouri-St. Louis with Professor Rudolph E. K. Winter on the synthesis of natural products.

Kumar Gadamasetti is currently the CEO of Certum Bio located in the San Francisco Bay area in CA-USA. Current interests are in the area of small molecules as well as biologics including Antibody Drug Conjugates (ADCs), building blocks of DNA and expanded genetic alphabet, and process chemistry related to biologics and small molecules. His professional career began at Bristol-Myers Squibb Co, followed by Amgen, Discovery Partners International, X-Mine. He was the founder of Delphian Pharmaceuticals and Certum LLC. He obtained his Ph.D. (1987) from the University of Vermont in organic chemistry of cancer drugs and precursors and has done post-doctoral work at the University of Virginia. He was the founder-chairman (2002-2004) of ACS Prospectives, ’Process Chemistry in the Pharmaceutical Industry’. He was the editor of two volumes titled, ’Process Chemistry in the Pharmaceutical Industry’ (ISBN# 0-8247-1981-6, 1999) and ’Process Chemistry in the Pharmaceutical Industry: Challenges in an Ever-Changing Climate’ (ISBN#13:978-0-8493-9051-7, 2007). Kumar has been a visiting professor at Catholic University at Louvain, Brussels, Belgium and the Univ. of Pittsburgh, PA-USA and was the invited speaker at Humboldt University, Berlin, Germany. His major accomplishments include his contributions on the development of drug substance (API) and the drug product that helped in launching three products to marketing: 1. Paclitaxel(R) (Bristol-Myers Squibb) 2. Sensipar(R) (Amgen) and 3. Duexis(R) (Horizon Therapeutics).

 

詳細資料

  • ISBN:9783031620065
  • 規格:精裝 / 490頁 / 普通級 / 初版
  • 出版地:美國
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