Digital twin technology is becoming important for the realization of Industry 4.0 using cyber-physical systems (CPS) and information technology. CPS form the backbone to support the creation of a network for decentralized and autonomous decision-making. The design principles for Industry 4.0 serve as guidelines for virtualization concepts that are virtual copies of the physical world and create a link between the real and virtual worlds to collect data and monitor processes, the so-called digital twin. In this book, a theoretical digital twin-driven decision-making model has been developed that combines corporate data quality management, a process digital twin, and a model-driven decision support system. It leverages the benefits of the digital twin to create, test and build a process in the virtual world that supports decision making by combining data, analytics and visualization of insights to help managers make better decisions