This research evaluated the production of Pleurotus ostreatus using coffee residues as an agroecological valorization alternative in the community of Shucush, Amazonas. Three residues derived from the coffee production cycle were selected: pulp, husk and concho, with which 16 substrate combinations were formulated in different proportions. The experimental design was completely randomized, covering 48 experimental units. The yield and earliness of P. ostreatus in each formulation were analyzed. The results revealed significant differences (p