This study examined the relationship between organizational socialization and individual work performance of general hospitals in Rivers State, Nigeria. The cross-sectional survey was adopted and a total population of seven hundred and ten (710) employees were covered. However, a total sample size of two hundred and forty-eight (248) employees was drawn from the population. The simple random sampling technique was utilized. The data were collected using copies of questionnaires and the Spearman Rank Order Correlation Coefficient was utilized in analyzing the retrieved data in order to ascertain the relationship between organizational socialization and individual work performance. The moderating influence of organizational culture on the relationship between organizational socialization and individual work performance was analyzed using the Partial correlation. The result revealed that there is a significant relationship between the dimensions of organizational socialization (anticipatory socialization, co-worker’s support and future prospect) with the measures of individual work performance (task performance, contextual performance and adaptive performance).