This research work was conducted under a descriptive and quantitative methodological approach and was applied to a simple random sample of 108 managers of small and medium enterprises (SMEs) located in the city of Hermosillo, Sonora, belonging to the commerce sector, with a labor force between 10 and 250 workers with a minimum seniority of five years in the market. The objective is to analyze the main difficulties and challenges faced by business management and how Information and Communication Technologies (ICT) influence the use of strategies in the administrative process. The main results show that the diagnosis carried out showed that, despite the fact that SME managers are aware of the benefits of using technological tools in business management, many of them show resistance to their implementation. As a final conclusion, globalization is currently generating constant transformations and, in order to remain in a highly competitive global environment, SMEs must enter the digital era and adopt information technologies within their administrative processes.