This research conceived Literature and Science as "sophias" whose worlds correlate, breaking with traditional paradigms about the vision of literature. The proposal consisted of bringing together two languages that are very particular due to their nature: the scientific and the humanistic. To this end, the short story "A Sign in Space" from Italo Calvino’s "The Cosmicomics" was used as a paradidactic approach to the textbook. Literature was seen in the work as a vehicle for disseminating science, allowing the general public to read and understand science through literature. As a didactic activity for the classroom, the work presented a lesson planning methodology for studying literature and science together. The science analysed was astronomy, a subject studied in the physics curriculum, according to the PCN-EM. The theoretical references found in the work were based on teachers who advocate literature in the physics teaching environment. As a result, it is hoped to promote an interest in research and to show MS students that different languages can dialogue with each other.