Senegal faces numerous challenges linked to coastal dynamics, climate change and the assessment of health risk factors. The coastline, a sea-land interface zone including the coastal strip, estuaries, deltas and the continental shelf, represents a strategic area for socio-economic development. It is exposed to a dual anthropogenic pressure (urban, industrial, agricultural, fishing and tourism) and climate change. In the current context of climate change and its corollaries, Senegal’s coastline is exposed to a number of risks and natural disasters, generating profound social, economic and environmental transformations that need to be analyzed in a holistic way, in order to understand the perception of different socio-cultural collectives of the links between climate change and natural disasters.