Currently, the actual problems of search and exploration of sulfur-free gas in the Ustyurt oil and gas bearing region attracts a lot of attention of scientists of the Republic of Uzbekistan. The analysis of previous studies on this problem shows that it is insufficiently studied. Taking into account today’s opportunities of information and communication technologies and digitalization, it is necessary to perform a deep analysis of localization of hydrocarbon resources in Ustyurt and Bukhara-Khiva oil and gas bearing regions (BKHNGR). In particular, as a result of geological exploration works (GWR) in the Kagan uplift of the BCNGR, oil, gas and gas condensate were obtained in the Shopulat, Sayozzhar, Turtkuduk and Zhumael areas in the Lower Cretaceous and Upper Jurassic sediments. Yorkin field was discovered on the Yangikazgan uplift, where gas and condensate were confined in Lower Cretaceous and Upper Jurassic sediments.The book is of great theoretical and practical interest for a wide range of scientists of oil and gas geology, conducting scientific research in the field of prospecting, exploration, development and operation of oil and gas fields, as well as doctoral students and students.