A field experiment entitled "Response of pre-released grain sorghum (Sorghum bicolar L. Moench) genotypes to different fertilizer levels" was undertaken during kharif, 2022-23 at Sorghum Research Station, Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani (Maharashtra). Results confirmed that the application of fertilizer plays a vital role in growth and yield of sorghum genotype. Genotype highly responsive to 150% RDF (120:60:60 NPK kg ha⁻ ) recorded higher growth attributes, yield attributes, grain yield, fodder yield, nutrient concentration and uptake, gross monetary and net monetary returns over 50 % and 0 % RDF. However, it was at par with 100% RDF. Hence application of 100 % RDF was found economically optimum and remunerative over rest of fertilizer levels.