In endodontics, navigation involves using various techniques and tools to locate, clean, and shape the root canals within a tooth, which is essential for successful root canal therapy. Key components include radiographic imaging (such as X-rays and CBCT) for detailed tooth anatomy, magnification and illumination through dental microscopes and loupes for enhanced visualization, and electronic apex locators (EALs) for accurate measurement of canal length. Specialized endodontic files and ultrasonic instruments are used to negotiate and shape the canals, while digital workflows and software aid in planning and precision. Effective navigation combines these advanced tools and techniques with the clinician’s expertise to ensure thorough cleaning and disinfection of the root canal system, preventing infection and ensuring long-term treatment success.