This book offers a thorough exploration of noisome, an innovative drug delivery system, encompassing their ultrastructure, different preparation techniques, and characterization. It also surveying their wide-ranging applications in various sectors. Detailed sections delve into niosomes’ efficacy in combating bacterial, parasitic, and fungal infections, providing valuable insights for advancing therapeutic strategies. The final chapter delves into prospective research avenues, establishing this resource as indispensable for researchers, healthcare professionals, and students engaged in drug delivery and antimicrobial treatment studies.