Role of Tissue-Specific Steroid Metabolism on Oral Health and Disease

Steroids play a crucial role in oral health by regulating inflammation and immune responses. Their metabolism within oral tissues influences both disease progression and treatment outcomes. Steroid-based therapies remain central in managing oral disorders like lichen planus, pemphigus, and periodontitis. However, their long-term use can cause systemic and local side effects, emphasizing the need for cautious administration. Emerging research on targeted steroid delivery and molecular mechanisms promises safer and more effective treatments in the future.