Ayurveda is a long-established Indian Medicinal System proficient for thousands of years. Huge research on pharmacognosy, chemistry, pharmacology and clinical the rapeutics has been carried out on ayurvedic medicinal plants. Kantakari (Solanum xanthocarpum Schrad. and Wendl & Solanum surattense Burm. f.) is very important plant used in ayurveda. This book mainly focusses on the compilation of ayurvedic Formulation, Properties, Therpuatic uses and pharmacology as per ayurveda and also all biological activity done as per modern science. Nearly 27 types (Antiasthmatic, Antifilarial, Antibacterial, Antifungal, Antioxidant, AntiHIV, Analgesic, Mosquito larvicidal effect, Antimalarial, Antihelmenthic, Anticancer/apoptosis, Antiobesity, Antiinflammatory, Antidiabetic, Hepatoprotective, Antiulcer, Wound healing, Diuretic activity, Antihyperlipedemic, Antifertility, Fertility, Antinociceptive, Antipiles, Psorasis, Anti Alzheimer, Biocidal Activity, Acute toxicity). This book play an important role in providing complete knowledge on S. xanthocarpum and S. surattense as an important natural source of many ethnomedicinal and pharmacological perspectives.