Of all the species that live on this planet, as far as we know, man is the only one capable of awareness; observing the sky, understanding its beauty, and asking questions about the meaning of life and that of death, on the beginning and the end, both about the Universe and man himself. The questions range in all directions: why is there something instead of nothing? Who is the architect of reality, and why does it appear to us as it does, rather than in some other way? What’s the point of all this? Where does life originate, and what are the origins of the Universe that encompasses it?This book aims to introduce and address the questions that are often asked and answer with the knowledge that science provides us. Where does all the matter we are made of come from and what constitutes the Universe? Is it true that there is matter and energy whose existence can be intuited only indirectly, as the existence of the wind is deduced from leaves’ motion? Einstein was right in his revolutionary description of reality, on nature of space and time, inextricable units in their apparent dichotomy. Does each observer truly observe a ’different’ time from another observer? Can we move back and forth in the time? How space and time are modified by astronomical objects such as black holes, and what is the nature of the latter? Will time and the Universe end and how did they originate? The Universe is incredibly vast, housing hundreds of billions of galaxies within the observable Universe alone. Beyond what we can observe, there may exist an unimaginably vast expanse that extends infinitely and beyond our imagination. Our Universe, enormous as it may be, is not the only one. That’s all predicted by certain cosmological and physical theories. Is life unique to Earth, or does the Universe harbor other forms of life that remain undiscovered to us? Finally, we are confronted with the most intriguing and elusive question of all: was all of this deliberately planned by some higher power, or is it merely a result of natural processes? Each of these questions touch on a fundamental aspect of our perception of the Universe and our quest to comprehend humanity’s place in the cosmos.