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Intra-uterine insemination (IUI) is a widely used fertility treatment for couples with unexplained and male subfertility. Although it is less invasive and less expensive than l other treatment options such as in vitro fertilization, several factors affect its outcome. In addition, IUI remains controversial due to concerns about some of the possible aspects of treatment, including side-effects such multiple pregnancies. This comprehensive evidence-based book from an international IUI expert team explores all of these topics and provides clear guidelines for daily practice.