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Monkey Pox, An Emerging Zoonotic Threat in the Modern Era provides a comprehensive analysis of Mpox, a re-emerging zoonotic disease that poses significant global health challenges. It explores the origins, transmission, and impact of Mpox on both human and animal populations, especially in the context of the COVID-19 pandemic. The book delves into diagnostic methods, treatment options, and vaccination strategies while addressing the complexities of managing simultaneous outbreaks. By incorporating insights from leading experts in virology, public health, and wildlife management, Mpox offers a thorough examination of innovative antiviral therapies, the role of wildlife in disease spread, and the socio-political factors influencing control efforts. It also highlights the need for improved global surveillance and collaboration to effectively manage zoonotic threats. Designed as a vital resource for healthcare professionals, researchers, and policymakers, this book aims to enhance understanding of Mpox and foster the development of effective strategies for preventing and controlling future outbreaks, ultimately contributing to global health security.