titare

Ameliorative Effect of Fluvastatin and Dapagliflozin on Vascular Endothelial Dysfunctionin Diabetic Rats: Metabolic syndrome can be defined as a cluster of interrelated risk factors that are associated with an increased risk of diabetes and cardiovascular disease. [1] It is estimated that around 20-25 per cent of the worlds adult population have the metabolic syndrome and they are three times as likely to have a heart attack or stroke compared with people without the syndrome. In addition, people with metabolic syndrome have a fivefold greater risk of developing type-2 diabetes. [2] Type-2 diabetes, which accounts for 90% of all diabetes, has become one of the major causes of premature illness and death, mainly through the increased risk of CVD which is responsible for up to 80% of deaths.