Hierzer

Amyotrophic lateral sclerosis is a neurological disease characterized by a progressive course with a fatal outcome, usually due to respiratory failure. The breakdown of the 1st and 2nd motor neurons leads to symptoms such as fatigue, muscle atrophy or paralysis in the human organism. Activities of daily living are restricted as the disease progresses and consequently the quality of life also decreases. As there are currently only a few effective drug therapies that have only a moderate influence on the increasing deterioration of the disease, it is important to be able to intervene with evidence-based physiotherapy using endurance and strength training. However, the effectiveness of non-pharmacological measures has only been sparsely investigated to date. In view of the current study situation, it can be assumed that individually tailored training is a good way for patients to maintain their physical functions at the activity and participation level and thus has a positive impact on their quality of life.