Isaac Ghebre-Selassie

　　This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms.

　　Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery

　　• describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions

　　• analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems

　　• details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules

　　• explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond

　　• previews the marketing considerations of multiparticulate systems in the years to come

　　• presents practical solutions to problems encountered in the area of film-coating processes

　　and more!