This paper uses a panel data approach to analyze the influence of endogenous sources of growth on the process of regional integration in the CEMAC zone. Using stata 11 software, we have estimated a model with a panel data sample of the six CEMAC member countries. The results show that the best sources of endogenous growth, sufficient to propel a new dynamic of regional integration in the CEMAC zone, are political stability, economic openness, public investment, public spending and the paving of roads for regional use.