Niles is a young kitten who, along with his mother and sister, are abandoned to fend for themselves in a big city neighbourhood. Distrustful and afraid, they are captured by a human rescue organization and are taken to their facility. The kind staff wins over their trust and prepares them for adoption into their perfect home. Along the way, Niles learns some important life lessons about love and friendship, the consequences of being adventurous and the importance of always being charming.